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American trypanosomiasis (Chagas disease) and the role of molecular epidemiology in guiding control strategies

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dc.rights.license Copyright © 2003, BMJ Publishing Group Ltd.
dc.contributor.author Rojas de Arias, Antonieta
dc.contributor.author Miles, Michael A.
dc.contributor.author Feliciangeli, M. Dora
dc.date.accessioned 2017-01-07T20:53:30Z
dc.date.available 2017-01-07T20:53:30Z
dc.date.issued 2003
dc.identifier.uri http://localhost:8080/xmlui-directorioacademico/handle/123456789/42
dc.description.abstract Chagas' disease is a parasitic infection that has far reaching consequences for public health and national economies in Latin America. The latest molecular typing methods may help in developing targeted, effective control programmes.
dc.description.abstract Summary points: Infection with Trypanosoma cruzi is a complex zoonosis, transmitted by many triatomine vector species and sustained by a multitude of mammalian reservoir hosts Widespread transmission in the wild (silvatic transmission) occurs in palm trees and other animal refuges that are infested with triatomine bugs; domestic transmission occurs where bugs colonise houses. Silvatic and domestic transmission cycles may be separate or overlap. Comparative genetics can resolve the extensive intraspecific diversity of T cruzi and can be applied to detect cryptic triatomine species. Unravelling transmission cycles by comparative genetics can guide the design of cost effective and improved control strategies.
dc.format application/pdf
dc.source British Medical Journal
dc.subject.mesh Animals
dc.subject.mesh Chagas
dc.subject.mesh Disease/epidemiology
dc.subject.mesh Chagas Disease/prevention & control
dc.subject.mesh Chagas Disease/transmission
dc.subject.mesh DNA, Protozoan/analysis
dc.subject.mesh Disease Vectors
dc.subject.mesh Forecasting
dc.subject.mesh Humans
dc.subject.mesh Insect Control
dc.subject.mesh Insect Vectors
dc.subject.mesh Parasitology/methods
dc.subject.mesh Species Specificity
dc.subject.mesh Triatominae/classification
dc.subject.mesh Triatominae/genetics
dc.subject.mesh Trypanosoma cruzi/genetics
dc.title American trypanosomiasis (Chagas disease) and the role of molecular epidemiology in guiding control strategies
dc.type Artículo
dcterms.bibliographicCitation BMJ. 2003 Jun 28; 326(7404): 1444–1448.
dc.source.volume 326
dc.source.volume 7404
dc.source.pages 1444 - 1448
dc.contributor.identifier 1261551
dc.identifier.doi 10.1136/bmj.326.7404.1444
dc.directorio.catalogador arv

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